Success rates with preimplantation genetic testing for aneuploidy in good prognosis patients are dependent on age
To evaluate cumulative live birth after preimplantation genetic testing for aneuploidy (PGT-A) with next generation sequencing (NGS) compared with morphology alone among patients aged 21–40 years undergoing single blastocyst transfer. Retrospective cohort study. Society for Assisted Reproductive Tec...
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Veröffentlicht in: | Fertility and sterility 2024-09 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To evaluate cumulative live birth after preimplantation genetic testing for aneuploidy (PGT-A) with next generation sequencing (NGS) compared with morphology alone among patients aged 21–40 years undergoing single blastocyst transfer.
Retrospective cohort study.
Society for Assisted Reproductive Technology (SART) clinics.
Patients aged 21–40 years undergoing first autologous retrieval cycles resulting in ≥5 fertilized oocytes, with subsequent single blastocyst transfer in Society for Assisted Reproductive Technology clinics from 2016–2019.
PGT-A using NGS.
The primary outcome was cumulative live birth per retrieval. Secondary outcomes included clinical pregnancy, miscarriage, and live birth per transfer.
A total of 56,469 retrieval cycles were included in the analysis. Retrieval cycles were stratified based on age ( |
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ISSN: | 0015-0282 1556-5653 1556-5653 |
DOI: | 10.1016/j.fertnstert.2024.09.043 |