Genomic profiling of selective sweeps through haplotype differentiation unravelled genes associated with production and reproduction traits in Indian goat breeds

A comprehensive genomic scan of selective sweeps was conducted in autochthonous Attappady Black and improved dual-purpose Malabari goat breeds in south India. High-throughput single nucleotide polymorphism (SNP) marker data, obtained through Illumina goat SNP50 BeadChip genotyping of 48 goats (24 ea...

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Veröffentlicht in:	Tropical animal health and production 2024-11, Vol.56 (8), p.296, Article 296
Hauptverfasser:	Thomas, Marykutty, G., Radhika, V., R. Thirupathy, V., Aravindakshan T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Breeding Casein Chromosome 6 Comparative analysis Differentiation Female Gene mapping Gene polymorphism Genes Genomic analysis Genomics Genotype Genotype & phenotype Genotyping Goats Goats - genetics Goats - physiology Haplotypes India Life Sciences Livestock Milk Milk production Nucleotides Polymorphism Polymorphism, Single Nucleotide Quantitative Trait Loci Regular Articles Reproduction Selection, Genetic Signal transduction Signature analysis Single-nucleotide polymorphism Veterinary Medicine/Veterinary Science Zoology
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Zusammenfassung:	A comprehensive genomic scan of selective sweeps was conducted in autochthonous Attappady Black and improved dual-purpose Malabari goat breeds in south India. High-throughput single nucleotide polymorphism (SNP) marker data, obtained through Illumina goat SNP50 BeadChip genotyping of 48 goats (24 each of Attappady Black and Malabari goats), were utilized for the analysis. Selection signature analysis, employing hapFLK analysis based on haplotype differentiation, identified seven significant sweep regions ( p
ISSN:	0049-4747 1573-7438 1573-7438
DOI:	10.1007/s11250-024-04136-2