Association between consumption of non-nutritive sweeteners and gestational diabetes mellitus in Chilean pregnant women: A secondary data analysis of the CHiMINCs-II cohort

•A total of 77.8% of Chilean pregnant women in the study consumed non-nutritive sweeteners (NNS) daily, with sucralose as the most prevalent.•Beverages are the main source of most NNS, while dairy and candies are significant for specific NNS.•Consumers f NNS had a higher risk of developing gestational diabetes mellitus (GDM) than non-consumers.•Sucralose was the only specific NNS associated with a higher GDM incidence in the study To evaluate the association between consumed non-nutritive sweeteners (NNS) and gestational diabetes mellitus (GDM) in a cohort of pregnant women from Santiago, Chile. This secondary data analysis of a cohort.involved 1,472 pregnant women from the Chilean Maternal-Infant Cohort Study-II (CHiMINCs-II). These women received care at primary health care centers in Puente Alto county, South-Eastern Metropolitan Health Service of Santiago, Chile. NNS consumption was estimated using 24-h dietary recalls and linked to the packaged foods nutrition facts panel. Plasma glucose values were extracted from clinical records. GDM was defined according to national criteria: 1) fasting plasma glucose (FPG) ≥100 and