Retinal electrophysiological alterations are associated with cognition in early course psychosis

Retinal electrophysiological alterations are associated with cognition in early course psychosis

Retinal electrophysiological alterations are implicated in psychosis, but their relationship with cognition in early course psychosis (ECP) is understudied. The Brief Assessment of Cognition (BAC) and flash electroretinography (fERG) were conducted in 24 controls (HC) and 27 ECP individuals. Partial...

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Veröffentlicht in:Schizophrenia research 2024-12, Vol.274, p.137-141
Hauptverfasser: Molho, Willa, Stiltner, Brendan, Raymond, Nicolas, Kiely, Chelsea, Trotti, Rebekah, Harris, Caroline, Bannai, Deepthi, Keshavan, Matcheri, Silverstein, Steven, Lizano, Paulo
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Cognition
Cognitive Dysfunction - etiology
Cognitive Dysfunction - physiopathology
Early course psychosis
Electroretinography
Female
Flash electroretinography
Humans
Male
Psychosis
Psychotic Disorders - physiopathology
Retina - physiopathology
Retinography
Young Adult
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Zusammenfassung:Retinal electrophysiological alterations are implicated in psychosis, but their relationship with cognition in early course psychosis (ECP) is understudied. The Brief Assessment of Cognition (BAC) and flash electroretinography (fERG) were conducted in 24 controls (HC) and 27 ECP individuals. Partial Spearman correlations were performed between fERG and BAC. Lower Photopic-1b and Scotopic-3b amplitudes were identified in ECP vs. HCs. Correlations were significant (p
ISSN:0920-9964
1573-2509
1573-2509
DOI:10.1016/j.schres.2024.09.013