Silver hair in a neonate: a tale of 2 fatal cases
Abstract Silver hair in a neonate is an uncommon occurrence. The aetiology of this condition is varied and is associated with immunodeficiency disorders such as Griscelli syndrome and Chédiak-Higashi syndrome. A preterm neonate with Griscelli syndrome type 2 might present with just silver colour sta...
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Veröffentlicht in: | Oxford Medical Case Reports 2024-09, Vol.2024 (9), p.omae106 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Abstract
Silver hair in a neonate is an uncommon occurrence. The aetiology of this condition is varied and is associated with immunodeficiency disorders such as Griscelli syndrome and Chédiak-Higashi syndrome. A preterm neonate with Griscelli syndrome type 2 might present with just silver colour staining of hair including the lanugo hair with no other complications. In those with associated systemic abnormalities such as congenital pulmonary airway malformation, further evaluation for conditions such as Menke-Kinke hair syndrome is required. In this case series, we describe two unique cases of silver hair syndrome in preterm neonates with their clinical description, course in the hospital, role of hair mount and genetic testing for further identification and diagnosis of this disorder. |
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ISSN: | 2053-8855 2053-8855 |
DOI: | 10.1093/omcr/omae106 |