Protein Intake and High Uric Acid Stone Risk

We evaluated the metabolic differences between pure and impure uric acid stone formers in this retrospective study of uric acid kidney stone formers diagnosed between 1996 and 2021. Demographics and medical history were compared by χ2 tests. Twenty-four-hour urine chemistries were compared using logistic regressions while controlling for demographics and comorbid conditions. Patients from Yale Urology and Nephrology Clinics with a documented kidney stone analysis containing uric acid were included. In total, 4,294 kidney stone formers had a stone analysis, and 722 (16.8%) contained uric acid. Patients with all stone analyses≥ 50% uric acid were allocated to the pure group, while patients with≥1 stone analysis