The role of DNA damage in diabetic complications

The role of DNA damage in diabetic complications

Mechanistic and clinical data indicate that DNA damage contributes to the pathogenesis and progression of diabetic complications. Thus, DNA damage and its signalling are entering the field of diabetology.

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Veröffentlicht in:Nature reviews. Endocrinology 2024-11, Vol.20 (11), p.629-630
Hauptverfasser: Kumar, Varun, Yildirim, Ali Önder, Nawroth, Peter P.
Format: Artikel
Sprache:eng
Schlagworte:
692/163/2743/137/138
692/699/317
Animals
Comment
Cytokines
Diabetes
Diabetes Complications - genetics
Diabetes mellitus
DNA Damage
DNA repair
Endocrinology
Enzymes
Epigenetics
Glucose
Humans
Insulin
Medicine
Medicine & Public Health
Metabolism
Metabolites
Pathogenesis
Pulmonology
Remission (Medicine)
Senescence
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Beschreibung
Zusammenfassung:Mechanistic and clinical data indicate that DNA damage contributes to the pathogenesis and progression of diabetic complications. Thus, DNA damage and its signalling are entering the field of diabetology.
ISSN:1759-5029
1759-5037
1759-5037
DOI:10.1038/s41574-024-01038-z