The effect of Momordica charantia extract on sheep infected with Haemonchus contortus

Bitter melon (Momordica charantia) has several biological properties including anthelmintic activity. Presented in vivo study evaluated the anthelmintic activity of the hydroalcoholic extract of M. charantia Presented in vivo study (HEMC) and its effect on animal performance, carcass characteristics and lamb meat quality in animals infected by Haemonchus contortus. The HEMC demonstrated effectiveness against the parasite. Lambs treated with HEMC showed a significant reduction in egg count per gram of faeces and in the number of parasites in the abomasum. However, nutrient intake decreased with increasing doses of HEMC, leading to reductions in final live weight and carcass weight. No significant effects were observed on meat quality. Therefore, it is concluded that HEMC presents anthelmintic action, but it also impairs animal performance, highlighting the need to assess the benefits and impacts of HEMC use for H. contortus control. [Display omitted] •Momordica charantia extract (HEMC) reduces lamb EPG counts.•Increasing HEMC doses lower nutrient intake and animal weight.•HEMC decreases adult H. contortus counts.•Higher HEMC doses reduce carcass weight, but meat quality is unaffected.