Exploring the Interplay Between Cannabinoids and Thymic Functions

Cannabinoids, derived from the Cannabis sativa plant, has garnered increasing attention for its potential therapeutic applications in various diseases. The pharmacologically active compounds in Cannabis, such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), exhibit diverse immunomodulato...

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Veröffentlicht in:Toxicological sciences 2024-11, Vol.202 (1), p.1-12
Hauptverfasser: Lins, Marvin Paulo, De Melo, Igor Santana
Format: Artikel
Sprache:eng
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Zusammenfassung:Cannabinoids, derived from the Cannabis sativa plant, has garnered increasing attention for its potential therapeutic applications in various diseases. The pharmacologically active compounds in Cannabis, such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), exhibit diverse immunomodulatory properties. While studies have explored the effects of cannabinoids on immune function, their specific interactions with the thymus, a primary immune organ critical for T cell development and maturation, remain an intriguing area of investigation. As the thymus plays a fundamental role in shaping the immune repertoire, understanding the interplay between cannabinoids and thymic function may shed light on potential benefits or concerns associated with Cannabis-based therapies. This article aims to provide an overview of the current scientific knowledge regarding the impact of medicinal Cannabis on the thymus and its implications for disease treatment and immune health.
ISSN:1096-6080
1096-0929
1096-0929
DOI:10.1093/toxsci/kfae114