Circulating immune complexes and G6PD deficiency predict readmissions for blackwater fever and severe anemia in children with severe malaria in Eastern Uganda

Circulating immune complexes and G6PD deficiency predict readmissions for blackwater fever and severe anemia in children with severe malaria in Eastern Uganda

Recently, there has been an unexplained increase in the incidence of blackwater fever (BWF) in Eastern Uganda. In this study, we evaluate the association between immune complexes, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and the occurrence and recurrence of BWF in children with severe ma...

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Veröffentlicht in:The Journal of infectious diseases 2024-08
Hauptverfasser: Namazzi, Ruth, Mellencamp, Kagan A, Opoka, Robert O, Datta, Dibyadyuti, Lima-Cooper, Giselle, Liepmann, Claire, Sherman, Julian, Rodriguez, Ana, Kazinga, Caroline, Ware, Russell E, Goings, Michael G, Lacerda, Marcus, Abreu, Marco, Schwantes-An, Tae-Hwi, John, Chandy C, Conroy, Andrea L
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Sprache:eng
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Zusammenfassung:Recently, there has been an unexplained increase in the incidence of blackwater fever (BWF) in Eastern Uganda. In this study, we evaluate the association between immune complexes, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and the occurrence and recurrence of BWF in children with severe malaria (SM). Between 2014 and 2017, children aged six months to
ISSN:1537-6613
1537-6613
DOI:10.1093/infdis/jiae431