Performance Characteristics of Next-Generation Sequencing-Based Engraftment Monitoring and Microchimerism Detection in Allogeneic Hematopoietic Cell Transplantation: A Practical Approach for Clinical Assay Validation

Performance Characteristics of Next-Generation Sequencing-Based Engraftment Monitoring and Microchimerism Detection in Allogeneic Hematopoietic Cell Transplantation: A Practical Approach for Clinical Assay Validation

Chimerism analysis by next-generation sequencing (NGS) is an emerging method for engraftment monitoring after allogeneic hematopoietic cell transplantation. A high-sensitivity method is required for the detection of microchimerism (

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Veröffentlicht in:The Journal of molecular diagnostics : JMD 2024-11, Vol.26 (11), p.995
Hauptverfasser: Blouin, Amanda G, Nelson, Wyatt, Geraghty, Daniel, Askar, Medhat, Ye, Fei
Format: Artikel
Sprache:eng
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Zusammenfassung:Chimerism analysis by next-generation sequencing (NGS) is an emerging method for engraftment monitoring after allogeneic hematopoietic cell transplantation. A high-sensitivity method is required for the detection of microchimerism (
ISSN:1943-7811
1943-7811
DOI:10.1016/j.jmoldx.2024.07.003