Expression characteristics of TBC1D4 activating protein molecule and identification of key module genes for preventing thyroid cancer progression

Expression characteristics of TBC1D4 activating protein molecule and identification of key module genes for preventing thyroid cancer progression

Endocrine tumors like thyroid carcinoma are becoming more frequent. No clinically informative predictors were found. Thus, effective gene networks and representative biomarkers can illuminate thyroid cancer prevention molecular mechanisms. TBC1D4 is an activating protein molecule that plays an impor...

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Veröffentlicht in:International journal of biological macromolecules 2024-10, Vol.278 (Pt 4), p.134986, Article 134986
Hauptverfasser: Wu, Na, Jing, Zuoqian, Lv, Huina, Liu, Qun, Gu, Ming, Zhong, Yifan, Xing, Peng, Ma, Ruiyang, Jing, Yuchen
Format: Artikel
Sprache:eng
Schlagworte:
Activating protein
Gene identification
Key modules
Molecular expression
Prevention progress
TBC1D4
Thyroid cancer
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Zusammenfassung:Endocrine tumors like thyroid carcinoma are becoming more frequent. No clinically informative predictors were found. Thus, effective gene networks and representative biomarkers can illuminate thyroid cancer prevention molecular mechanisms. TBC1D4 is an activating protein molecule that plays an important role in regulating cell metabolism and signal transduction. The aim of this study was to investigate the expression characteristics of TBC1D4 activating protein molecules and identify key module genes that prevent thyroid cancer progression. GSE65144 data were downloaded from GEO. “limma” in R found DEGs with a false discovery rate 
ISSN:0141-8130
1879-0003
1879-0003
DOI:10.1016/j.ijbiomac.2024.134986