Microglia-mediated neuroimmune suppression in PTSD is associated with anhedonia

Dynamic brain immune function in individuals with posttraumatic stress disorder is rarely studied, despite evidence of peripheral immune dysfunction. Positron emission tomography brain imaging using the radiotracer [ C]PBR28 was used to measure the 18-kDa translocator protein (TSPO), a microglial ma...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2024-08, Vol.121 (35), p.e2406005121
Hauptverfasser: Bonomi, Robin, Hillmer, Ansel T, Woodcock, Eric, Bhatt, Shivani, Rusowicz, Aleksandra, Angarita, Gustavo A, Carson, Richard E, Davis, Margaret T, Esterlis, Irina, Nabulsi, Nabeel, Huang, Yiyun, Krystal, John H, Pietrzak, Robert H, Cosgrove, Kelly P
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Sprache:eng
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