Mechanistic study of NUPR1 in bladder cancer development through transcriptional regulation of CCR2

Nuclear protein‐1 (NUPR1) (also known as p8) is one of the genes associated with transcription factors that participate in various aspects of cancer initiation and development. However, the molecular mechanisms of NUPR1 in bladder cancer (BLCA) remain unclear. We conducted an analysis of the correla...

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Veröffentlicht in:	Journal of cellular physiology 2024-11, Vol.239 (11), p.e31412-n/a
Hauptverfasser:	Shi, Zebin, Mi, Yuanyuan, Zhang, Li, Zhang, Wenxu, Zhang, Wei, Shi, Xiaokai, Gao, Shenglin, Zuo, Li, Zhang, Lifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal research Animals Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Bladder Bladder cancer Cancer CC chemokine receptors CCAAT/enhancer-binding protein CCR2 Cell Line, Tumor Cell Proliferation - genetics Chemokine receptors Chromatin Correlation Experiments Gene expression Gene Expression Regulation, Neoplastic - genetics Gene regulation Genes Humans Immunofluorescence Immunoprecipitation invasion Mice Mice, Nude Molecular modelling Neoplasm Proteins - genetics Neoplasm Proteins - metabolism NUPR1 Proteins Receptors, CCR2 - genetics Receptors, CCR2 - metabolism siRNA Staining Transcription factors Transcription, Genetic transcriptional Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
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