Epidemiology of lipid disturbances in psoriasis: An analysis of trends from 2006 to 2023

A strong link has been established between psoriasis and lipid disturbances; however, no study has systematically examined their global epidemiology. We searched six databases from their inception up to October 1, 2023. Data analysis was conducted using Stata SE 15.1. We performed subgroup, meta-regression, and sensitivity analyses to assess the heterogeneity of the pooled studies. Our review included 239 studies comprising 15,519,570 participants. The pooled prevalence rate of dyslipidemia among individuals with psoriasis was 38%. Patients with severe psoriasis should undergo screening for lipid abnormalities. This can facilitate the early detection of lipid dysfunction and associated cardiovascular comorbidities. •We investigated psoriasis's impact on lipids and country-specific differences using observational studies from 2006 to 2023.