Assessment of blood viral load in asymptomatic and symptomatic cases of congenital cytomegalovirus infection

This study aimed to retrospectively evaluate the baseline and follow‐up viral loads and viral clearance times in cases followed for asymptomatic and symptomatic congenital cytomegalovirus (cCMV) infection between August 2010 and August 2022. Among 93 cases, they had asymptomatic (n: 55) and symptoma...

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Veröffentlicht in:	Journal of medical virology 2024-08, Vol.96 (8), p.e29853-n/a
Hauptverfasser:	Güneş, Ömer, Gülhan, Belgin, Üçkardeş, Fatih, Güney, Ahmet Yasin, Coşkun, Zehra Nihan, Özen, Seval, Kanık‐Yüksek, Saliha, Özkaya‐Parlakay, Aslınur
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - therapeutic use Asymptomatic Asymptomatic Infections Blood congenital cytomegalovirus Cytomegalovirus Cytomegalovirus - genetics Cytomegalovirus - isolation & purification Cytomegalovirus Infections - blood Cytomegalovirus Infections - congenital Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - virology Female Humans Infant Infant, Newborn Infections Male Retrospective Studies symptomatic viral clearance Viral Load Viremia - virology
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Zusammenfassung:	This study aimed to retrospectively evaluate the baseline and follow‐up viral loads and viral clearance times in cases followed for asymptomatic and symptomatic congenital cytomegalovirus (cCMV) infection between August 2010 and August 2022. Among 93 cases, they had asymptomatic (n: 55) and symptomatic (n: 38). The median baseline blood viral load detected in the symptomatic cCMV (ScCMV) infection (13 054 IU/mL) was significantly higher than that of asymptomatic cCMV (AcCMV) infection (4636 IU/mL) (p
ISSN:	0146-6615 1096-9071 1096-9071
DOI:	10.1002/jmv.29853