Improving genetic testing utilization in a tertiary care neonatal intensive care unit through quality improvement
There is an increasing recognition of the importance of diagnosing genetic conditions with an ever‐growing list of genetic testing options. However, most providers do not have formal genetics training, which makes choosing the most appropriate test to order challenging. Our project sought to improve...
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Veröffentlicht in: | American journal of medical genetics. Part A 2024-12, Vol.194 (12), p.e63834-n/a |
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container_title | American journal of medical genetics. Part A |
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creator | Jacobsmeyer, Andrew T. Buitrago‐Mogollon, Talia L. White, Blanche Charles, Jasmyne‐Rian Clarke‐Pounder, Jessica P. Amador, Jodi Carter, Lauren B. |
description | There is an increasing recognition of the importance of diagnosing genetic conditions with an ever‐growing list of genetic testing options. However, most providers do not have formal genetics training, which makes choosing the most appropriate test to order challenging. Our project sought to improve cytogenetic testing utilization in a tertiary care neonatal intensive care unit (NICU) through utilizing quality improvement techniques, specifically the Model for Improvement framework with rapid Plan‐Do‐Study‐Act cycles. Our project utilized various interventions including the implementation of a NICU genetic testing algorithm. Interventions demonstrated improvement in all areas, specifically a 92% reduction in unnecessary cytogenetic testing with improvement in the diagnostic rate. Our work also resulted in a 59% decrease in charges with an estimated projected savings of $21,000 per year. Quality improvement can minimize redundancies and inefficiencies in genetic testing in a Level IV NICU in a large tertiary care children's hospital and result in substantial cost‐savings. |
doi_str_mv | 10.1002/ajmg.a.63834 |
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Part A</title><addtitle>Am J Med Genet A</addtitle><description>There is an increasing recognition of the importance of diagnosing genetic conditions with an ever‐growing list of genetic testing options. However, most providers do not have formal genetics training, which makes choosing the most appropriate test to order challenging. Our project sought to improve cytogenetic testing utilization in a tertiary care neonatal intensive care unit (NICU) through utilizing quality improvement techniques, specifically the Model for Improvement framework with rapid Plan‐Do‐Study‐Act cycles. Our project utilized various interventions including the implementation of a NICU genetic testing algorithm. Interventions demonstrated improvement in all areas, specifically a 92% reduction in unnecessary cytogenetic testing with improvement in the diagnostic rate. Our work also resulted in a 59% decrease in charges with an estimated projected savings of $21,000 per year. Quality improvement can minimize redundancies and inefficiencies in genetic testing in a Level IV NICU in a large tertiary care children's hospital and result in substantial cost‐savings.</description><subject>Cytogenetics</subject><subject>Genetic screening</subject><subject>Genetic testing</subject><subject>Genetic Testing - economics</subject><subject>Genetic Testing - methods</subject><subject>Genetic Testing - standards</subject><subject>genetic testing utilization</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Intensive care</subject><subject>Intensive Care Units, Neonatal</subject><subject>microarray</subject><subject>Neonates</subject><subject>neonatology</subject><subject>pediatrics</subject><subject>Quality control</subject><subject>Quality Improvement</subject><subject>Tertiary Care Centers</subject><subject>Tertiary Healthcare</subject><issn>1552-4825</issn><issn>1552-4833</issn><issn>1552-4833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kT1v2zAQhokiReOm3TIHBLJkiF1-SZFGw0jcFCm6tDNxok4ODYmyScqB--tLW06GDJ2Od_fgveO9hFxyNuOMiW-w7lYzmOWykOoDmfAsE1NVSHn29hbZOfkcwpoxybK7_BM5lyWXolR8QraP3cb3O-tWdIUOozU0YoiHfIi2tX8h2t5R6yikho8W_J4a8Egd9g4itKkX0QW7w7E-OBtpfPb9sHqm2wFaG_fUHqdghy5-IR8baAN-PcUL8ufh_vfi-_Tp1_JxMX-aGim4mgJXeWZyKMDUFaDJlamzgjGDZcELUVSS56apmhqNaIoKoL7jQjWiVmXNGg7ygtyMumnydkh_0p0NBtsW0uZD0JKVgnHJmUro9Tt03Q_epe20TKK8VLJkibodKeP7EDw2euNtl-6hOdMHK_TBCg36aEXCr06iQ9Vh_Qa_3j4BagRebIv7_4rp-Y-fy_mo-w_TNpht</recordid><startdate>202412</startdate><enddate>202412</enddate><creator>Jacobsmeyer, Andrew T.</creator><creator>Buitrago‐Mogollon, Talia L.</creator><creator>White, Blanche</creator><creator>Charles, Jasmyne‐Rian</creator><creator>Clarke‐Pounder, Jessica P.</creator><creator>Amador, Jodi</creator><creator>Carter, Lauren B.</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0006-0381-4159</orcidid></search><sort><creationdate>202412</creationdate><title>Improving genetic testing utilization in a tertiary care neonatal intensive care unit through quality improvement</title><author>Jacobsmeyer, Andrew T. ; Buitrago‐Mogollon, Talia L. ; White, Blanche ; Charles, Jasmyne‐Rian ; Clarke‐Pounder, Jessica P. ; Amador, Jodi ; Carter, Lauren B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3214-a1465c6a8acdbaec64cd5800ce981828b316cfbfdec2f8baad7124f2d49d0f1a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Cytogenetics</topic><topic>Genetic screening</topic><topic>Genetic testing</topic><topic>Genetic Testing - economics</topic><topic>Genetic Testing - methods</topic><topic>Genetic Testing - standards</topic><topic>genetic testing utilization</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Intensive care</topic><topic>Intensive Care Units, Neonatal</topic><topic>microarray</topic><topic>Neonates</topic><topic>neonatology</topic><topic>pediatrics</topic><topic>Quality control</topic><topic>Quality Improvement</topic><topic>Tertiary Care Centers</topic><topic>Tertiary Healthcare</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jacobsmeyer, Andrew T.</creatorcontrib><creatorcontrib>Buitrago‐Mogollon, Talia L.</creatorcontrib><creatorcontrib>White, Blanche</creatorcontrib><creatorcontrib>Charles, Jasmyne‐Rian</creatorcontrib><creatorcontrib>Clarke‐Pounder, Jessica P.</creatorcontrib><creatorcontrib>Amador, Jodi</creatorcontrib><creatorcontrib>Carter, Lauren B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of medical genetics. Part A</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jacobsmeyer, Andrew T.</au><au>Buitrago‐Mogollon, Talia L.</au><au>White, Blanche</au><au>Charles, Jasmyne‐Rian</au><au>Clarke‐Pounder, Jessica P.</au><au>Amador, Jodi</au><au>Carter, Lauren B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improving genetic testing utilization in a tertiary care neonatal intensive care unit through quality improvement</atitle><jtitle>American journal of medical genetics. Part A</jtitle><addtitle>Am J Med Genet A</addtitle><date>2024-12</date><risdate>2024</risdate><volume>194</volume><issue>12</issue><spage>e63834</spage><epage>n/a</epage><pages>e63834-n/a</pages><issn>1552-4825</issn><issn>1552-4833</issn><eissn>1552-4833</eissn><abstract>There is an increasing recognition of the importance of diagnosing genetic conditions with an ever‐growing list of genetic testing options. However, most providers do not have formal genetics training, which makes choosing the most appropriate test to order challenging. Our project sought to improve cytogenetic testing utilization in a tertiary care neonatal intensive care unit (NICU) through utilizing quality improvement techniques, specifically the Model for Improvement framework with rapid Plan‐Do‐Study‐Act cycles. Our project utilized various interventions including the implementation of a NICU genetic testing algorithm. Interventions demonstrated improvement in all areas, specifically a 92% reduction in unnecessary cytogenetic testing with improvement in the diagnostic rate. Our work also resulted in a 59% decrease in charges with an estimated projected savings of $21,000 per year. 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subjects | Cytogenetics Genetic screening Genetic testing Genetic Testing - economics Genetic Testing - methods Genetic Testing - standards genetic testing utilization Humans Infant, Newborn Intensive care Intensive Care Units, Neonatal microarray Neonates neonatology pediatrics Quality control Quality Improvement Tertiary Care Centers Tertiary Healthcare |
title | Improving genetic testing utilization in a tertiary care neonatal intensive care unit through quality improvement |
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