GDF11 (Protein of Juvenility) and GDF15 (Protein of Senility) in the Plasma of Patients with Sleep Apnea Syndrome: a Pilot Study

GDF11 (Protein of Juvenility) and GDF15 (Protein of Senility) in the Plasma of Patients with Sleep Apnea Syndrome: a Pilot Study

We performed a matched-pair analysis of the content of GDF11 and GDF15 proteins in the plasma of patients (56 middle-aged men) with obstructive sleep apnea syndrome (OSAS) and healthy volunteers (27 men with no complaints of sleep disorders). The groups were comparable in terms of age and presence o...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2024-06, Vol.177 (2), p.274-277
Hauptverfasser: Madaeva, I. M., Titova, E. V., Berdina, O. N., Sholokhov, L. F., Semenova, N. V., Kolesnikov, S. I., Kolesnikova, L. I.
Format: Artikel
Sprache:eng
Schlagworte:
Aging
Apnea
Biogerontology
Biomedical and Life Sciences
Biomedicine
Cell Biology
Chronic illnesses
Disease
Geriatrics
Growth factors
Heart attacks
Hypertension
Hypoxia
Internal Medicine
Laboratory Medicine
Middle age
Pathology
Pilot projects
Plasma
Proteins
Sleep apnea
Sleep disorders
Statistical analysis
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Zusammenfassung:We performed a matched-pair analysis of the content of GDF11 and GDF15 proteins in the plasma of patients (56 middle-aged men) with obstructive sleep apnea syndrome (OSAS) and healthy volunteers (27 men with no complaints of sleep disorders). The groups were comparable in terms of age and presence of chronic diseases. No statistically significant differences in GDF11 content in the studied groups were revealed, while the content of GDF15 in the OSAS group was 1.3 times higher. These results require further research from the viewpoint of geriatric somnology and molecular biology
ISSN:0007-4888
1573-8221
1573-8221
DOI:10.1007/s10517-024-06172-2