Validation of an AI-Powered Automated X-ray Bone Age Analyzer in Chinese Children and Adolescents: A Comparison with the Tanner–Whitehouse 3 Method

Introduction Automated bone age assessment (BAA) is of growing interest because of its accuracy and time efficiency in daily practice. In this study, we validated the clinical applicability of a commercially available artificial intelligence (AI)-powered X-ray bone age analyzer equipped with a deep...

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Veröffentlicht in:Advances in therapy 2024-09, Vol.41 (9), p.3664-3677
Hauptverfasser: Liang, Yan, Chen, Xiaobo, Zheng, Rongxiu, Cheng, Xinran, Su, Zhe, Wang, Xiumin, Du, Hongwei, Zhu, Min, Li, Guimei, Zhong, Yan, Cheng, Shengquan, Yu, Baosheng, Yang, Yu, Chen, Ruimin, Cui, Lanwei, Yao, Hui, Gu, Qiang, Gong, Chunxiu, Jun, Zhang, Huang, Xiaoyan, Liu, Deyun, Yan, Xueqin, Wei, Haiyan, Li, Yuwen, Zhang, Huifeng, Liu, Yanjie, Wang, Fengyun, Zhang, Gaixiu, Fan, Xin, Dai, Hongmei, Luo, Xiaoping
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Sprache:eng
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Zusammenfassung:Introduction Automated bone age assessment (BAA) is of growing interest because of its accuracy and time efficiency in daily practice. In this study, we validated the clinical applicability of a commercially available artificial intelligence (AI)-powered X-ray bone age analyzer equipped with a deep learning-based automated BAA system and compared its performance with that of the Tanner–Whitehouse 3 (TW-3) method. Methods Radiographs prospectively collected from 30 centers across various regions in China, including 900 Chinese children and adolescents, were assessed independently by six doctors (three experts and three residents) and an AI analyzer for TW3 radius, ulna, and short bones (RUS) and TW3 carpal bone age. The experts’ mean estimates were accepted as the gold standard. The performance of the AI analyzer was compared with that of each resident. Results For the estimation of TW3-RUS, the AI analyzer had a mean absolute error (MAE) of 0.48 ± 0.42. The percentage of patients with an absolute error of
ISSN:0741-238X
1865-8652
1865-8652
DOI:10.1007/s12325-024-02944-4