Angiotensin converting enzyme inhibitory hydrolysate and peptide fractions from chicken skin collagen, as modulators of lipid accumulation in adipocytes 3 T3-L1, after in vitro gastrointestinal digestion

Angiotensin converting enzyme inhibitory hydrolysate and peptide fractions from chicken skin collagen, as modulators of lipid accumulation in adipocytes 3 T3-L1, after in vitro gastrointestinal digestion

Inhibitory activity against angiotensin-converting enzyme (IAACE) by chicken skin collagen hydrolysate (CSCH) and their peptide fractions before and after in-vitro gastrointestinal digestion, were evaluated; as well as their ability to modulate lipid accumulation in 3 T3-L1 adipocytes. Before digest...

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Veröffentlicht in:Food chemistry 2024-12, Vol.460 (Pt 2), p.140551, Article 140551
Hauptverfasser: González-Noriega, Julio Alfonso, Valenzuela-Melendres, Martín, Hernández-Mendoza, Adrián, Astiazarán-García, Humberto, Islava-Lagarda, Thalia, Tortoledo-Ortiz, Orlando, Huerta-Ocampo, José Ángel, de La Garza, Ana Laura, Peña-Ramos, Etna Aída
Format: Artikel
Sprache:eng
Schlagworte:
3T3-L1 Cells
3 T3-L1 adipocyte
Adipocytes - drug effects
Adipocytes - metabolism
Angiotensin converting enzyme
Angiotensin-Converting Enzyme Inhibitors - chemistry
Angiotensin-Converting Enzyme Inhibitors - metabolism
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Animals
Chickens - metabolism
Collagen - chemistry
Collagen - metabolism
Collagen hydrolysate
Digestion
Gastrointestinal digestion
Gastrointestinal Tract - metabolism
Humans
Lipid Metabolism - drug effects
Mice
Peptides - chemistry
Peptides - metabolism
Peptides - pharmacology
Peptides fractions
Peptidyl-Dipeptidase A - chemistry
Peptidyl-Dipeptidase A - metabolism
Protein Hydrolysates - chemistry
Protein Hydrolysates - metabolism
Protein Hydrolysates - pharmacology
Skin - chemistry
Skin - metabolism
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Zusammenfassung:Inhibitory activity against angiotensin-converting enzyme (IAACE) by chicken skin collagen hydrolysate (CSCH) and their peptide fractions before and after in-vitro gastrointestinal digestion, were evaluated; as well as their ability to modulate lipid accumulation in 3 T3-L1 adipocytes. Before digestion, peptide fraction
ISSN:0308-8146
1873-7072
1873-7072
DOI:10.1016/j.foodchem.2024.140551