Monitoring of Specific Phytoestrogens by Dedicated Electrochemical Sensors: A Review

Phytoestrogens are non-steroidal estrogens produced from plants that can bind with the human body's estrogenic receptor site and be used as a substitute for maintaining hormonal balance. They are mainly classified as flavonoids, phenolic acids, lignans, stilbenes, and coumestans; some are resocyclic acids of lactones, which are mycotoxins and not natural phytoestrogen. Phytoestrogens have many beneficial medicinal properties, making them an important part of the daily diet. Electrochemical sensors are widely used analytical tools for analysing various pharmaceuticals, chemicals, pollutants and food items. Electrochemical sensors provide an extensive platform for highly sensitive and rapid analysis. Several reviews have been published on the importance of the biological and medicinal properties of phytoestrogens. However, this review provides an overview of recent work performed through electrochemical measurements with electrochemical sensors and biosensors for all the classes of phytoestrogens done so far since 2019. •Phytoestrogens, their classification and sources have been discussed.•Electrochemical sensors for phytoestrogens in food samples and dietary supplements.•First comprehensive review of the electrochemical assay of dietary phytoestrogens.•The advantages of new generation electrochemical sensors for phytoestrogens.•Point-of-care testing for rapid test and home test for phytoestrogens in food samples.