How does the spliceosome dismantle itself?

Precursor messenger RNA is edited into its final form by an RNA–protein assembly called the spliceosome. Structural evidence provides insights into how the spliceosome is disassembled when its job is complete. Structural evidence reveals key steps during spliceosome disassembly.

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Veröffentlicht in:	Nature (London) 2024-08, Vol.632 (8024), p.261-262
Hauptverfasser:	Shi, Shasha, Zhao, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	631/45 631/535 Animals Catalysis Electron microscopy Humanities and Social Sciences Humans Hypotheses Intermediates Microscopy multidisciplinary News And Views Proteins RNA Splicing Science snRNA Spliceosomes - metabolism Transmission electron microscopy Yeast Yeasts
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Precursor messenger RNA is edited into its final form by an RNA–protein assembly called the spliceosome. Structural evidence provides insights into how the spliceosome is disassembled when its job is complete. Structural evidence reveals key steps during spliceosome disassembly.
ISSN:	0028-0836 1476-4687 1476-4687
DOI:	10.1038/d41586-024-02327-3