What is needed to achieve effective and sustainable control of African animal trypanosomosis?

International, cross-sectorial, and interdisciplinary efforts are providing opportunities to involve all stakeholders in shaping research and policy priorities. Coordinated approaches offer hope for arriving at sustainable control of African animal trypanosomosis (AAT).Strategic frameworks (e.g., the Progressive Control Pathway) have been developed that can provide coherence across international and national control efforts against AAT.A benzoxaborole compound is in development, providing the prospect of the first novel trypanocide in >60 years.Fundamental advances have improved the ability to work with clinically relevant trypanosome species, enhancing research capacity for identifying drug candidates, and understanding drug mechanisms of action and resistance.Improving integration of efforts across all stakeholder sectors will ensure that advances translate to meaningful strategies and impact in the field. A welcome resurgence in African animal trypanosomosis (AAT) research has resulted in advances in capabilities, foundational datasets, and understanding. Additionally, there is the prospect of the first new trypanocide in >60 years. However, it is vital to ensure that advances translate to improved and sustainable control in the field. A recent meeting, the Symposium on African Livestock Trypanosomes – Tanzania, convened stakeholders from across the spectrum of AAT research and control to ask how this can be achieved. Current constraints on progress were defined, as were critical gaps and opportunities that need addressing. There is a requirement and opportunity for the AAT research community to communicate, collaborate, and coordinate to maintain momentum and achieve the ultimate goal of sustainable AAT control. A welcome resurgence in African animal trypanosomosis (AAT) research has resulted in advances in capabilities, foundational datasets, and understanding. Additionally, there is the prospect of the first new trypanocide in >60 years. However, it is vital to ensure that advances translate to improved and sustainable control in the field. A recent meeting, the Symposium on African Livestock Trypanosomes – Tanzania, convened stakeholders from across the spectrum of AAT research and control to ask how this can be achieved. Current constraints on progress were defined, as were critical gaps and opportunities that need addressing. There is a requirement and opportunity for the AAT research community to communicate, collaborate, and coordinate to mainta