Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in Plasmodium falciparum

A highly effective vaccine for malaria remains an elusive target, at least in part due to the under-appreciated natural parasite variation. This study aimed to investigate genetic and structural variation, and immune selection of leading malaria vaccine candidates across the Plasmodium falciparum�...

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Veröffentlicht in:EBioMedicine 2024-08, Vol.106, p.105227, Article 105227
Hauptverfasser: Ciubotariu, Ilinca I., Broyles, Bradley K., Xie, Shaojun, Thimmapuram, Jyothi, Mwenda, Mulenga C., Mambwe, Brenda, Mulube, Conceptor, Matoba, Japhet, Schue, Jessica L., Moss, William J., Bridges, Daniel J., He, Qixin, Carpi, Giovanna
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Sprache:eng
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