Reduction hits the sweet spot: A revised biosynthesis of dolichol

Reduction hits the sweet spot: A revised biosynthesis of dolichol

Dolichol is a lipid that is involved in protein glycosylation, a process that is essential for all eukaryotic life. In this issue of Cell, Wilson and coworkers1 report how a rare human genetic disorder led to the discovery of dolichol biosynthesis. Dolichol is a lipid that is involved in protein gly...

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Veröffentlicht in:Cell 2024-07, Vol.187 (14), p.3502-3503
1. Verfasser: O’Connor, Sarah E.
Format: Artikel
Sprache:eng
Schlagworte:
Dolichols - biosynthesis
Dolichols - metabolism
Glycosylation
Humans
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Zusammenfassung:Dolichol is a lipid that is involved in protein glycosylation, a process that is essential for all eukaryotic life. In this issue of Cell, Wilson and coworkers1 report how a rare human genetic disorder led to the discovery of dolichol biosynthesis. Dolichol is a lipid that is involved in protein glycosylation, a process that is essential for all eukaryotic life. In this issue of Cell, Wilson and coworkers report how a rare human genetic disorder led to the discovery of dolichol biosynthesis.
ISSN:0092-8674
1097-4172
1097-4172
DOI:10.1016/j.cell.2024.05.006