Aliphatic Hydrosilanes via Nickel-Catalyzed Reductive Csp3–Si Coupling of Primary Alkyl Bromides and Chlorohydrosilanes

The reductive C–Si coupling of chlorosilanes offers efficient access to organosilanes, but its potential for constructing aliphatic ones remains largely unexplored. This manuscript presents a nickel-catalyzed Csp3–Si coupling reaction of unactivated alkyl–Br and R2Si­(H)­Cl. This work establishes a new approach for synthesizing highly functionalized aliphatic hydrosilanes from readily available chemical feedstocks. The reaction is easily scalable and can accommodate various functional groups, including carboxylic acids, which are usually incompatible with basic conditions.