Chameleon impersonation of NK cells and ILC1s

Innate lymphoid cells (ILCs) exhibit remarkable plasticity, which makes using definitive markers to distinguish non-cytotoxic ILC1s and NK cells across different tissues difficult. New research now shows how the tissue microenvironments imprint diverse phenotypes that result in ILC1s and NK cells im...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature immunology 2024-08, Vol.25 (8), p.1313-1315
Hauptverfasser:	Chaudhry, M. Zeeshan, Belz, Gabrielle T.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2504 631/250/2504/2506 Animals Antigens Biomedical and Life Sciences Biomedicine Blood Cells Cytotoxicity Humans Immunology Infectious Diseases Killer Cells, Natural - immunology Lymphoid cells Lymphoid Progenitor Cells - cytology Lymphoid Progenitor Cells - immunology Lymphoid Progenitor Cells - metabolism Mice Microenvironments News & Views news-and-views Phenotypes Phenotypic plasticity Proteins Transcription factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Innate lymphoid cells (ILCs) exhibit remarkable plasticity, which makes using definitive markers to distinguish non-cytotoxic ILC1s and NK cells across different tissues difficult. New research now shows how the tissue microenvironments imprint diverse phenotypes that result in ILC1s and NK cells imitating each other.
ISSN:	1529-2908 1529-2916 1529-2916
DOI:	10.1038/s41590-024-01886-x