Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply
Short prolongation of waiting time seems to be less important than the presence of appendicolith for perforation risk; however, the predetermined power calculations did not cover this subgroup analysis, and patient-specific evaluation should be used when applying the results. A modified per-protocol...
Gespeichert in:
| Veröffentlicht in: | The Lancet (British edition) 2024-06, Vol.403 (10445), p.2693-2694 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2694 |
|---|---|
| container_issue | 10445 |
| container_start_page | 2693 |
| container_title | The Lancet (British edition) |
| container_volume | 403 |
| creator | Jalava, Karoliina Sallinen, Ville Mentula, Panu |
| description | Short prolongation of waiting time seems to be less important than the presence of appendicolith for perforation risk; however, the predetermined power calculations did not cover this subgroup analysis, and patient-specific evaluation should be used when applying the results. A modified per-protocol analysis was performed to mitigate possible bias, and no statistically significant difference to the results was found. VS has received research grants from the Helsinki University Hospital. |
| doi_str_mv | 10.1016/S0140-6736(24)00640-8 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3071283219</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0140673624006408</els_id><sourcerecordid>3070412189</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1866-880ef4de5c030d73f6362bee21bf6cf6a12347914ca347e032322618d79f502a3</originalsourceid><addsrcrecordid>eNqFkM9KJDEQh4O46OjuI6wEPKiHdit_Op3xIjKM7oKgqCt7C5mkGiM93W3SLczNd_ANfRJ7HPWwF09Fwff7VfER8pPBIQOmfl0Dk5CpQqh9Lg8A1LDpNTJispBZLot_62T0iWySrZTuAUAqyDfIptBj0LpQI3J7GbFpMdouPCL1WNkFDTXta9fM2yo426Gntm2x9sGFLqQj2t0hvZxenU4nN7SLwVb05emZnvTdXRPTHo3YVovv5Ftpq4Q_3uc2-Xs6vZn8zs4vzv5MTs4zx7RSmdaApfSYOxDgC1EqofgMkbNZqVypLONCFmMmnR0mguCCc8W0L8ZlDtyKbbK_6m1j89Bj6sw8JIdVZWts-mQEFIxrwdl4QHf_Q--bPtbDd0sKJONML6l8RbnYpBSxNG0McxsXhoFZijdv4s3SquHSvIk3esjtvLf3szn6z9SH6QE4XgE46HgMGE1yAWuHPkR0nfFN-OLEK9ynkRo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3070412189</pqid></control><display><type>article</type><title>Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>ProQuest Central UK/Ireland</source><creator>Jalava, Karoliina ; Sallinen, Ville ; Mentula, Panu</creator><creatorcontrib>Jalava, Karoliina ; Sallinen, Ville ; Mentula, Panu</creatorcontrib><description>Short prolongation of waiting time seems to be less important than the presence of appendicolith for perforation risk; however, the predetermined power calculations did not cover this subgroup analysis, and patient-specific evaluation should be used when applying the results. A modified per-protocol analysis was performed to mitigate possible bias, and no statistically significant difference to the results was found. VS has received research grants from the Helsinki University Hospital.</description><identifier>ISSN: 0140-6736</identifier><identifier>ISSN: 1474-547X</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(24)00640-8</identifier><identifier>PMID: 38908876</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Antibiotics ; Appendectomy ; Appendicitis ; Appendicitis - surgery ; Humans ; Older people ; Patients ; Preoperative Care - methods ; Prolongation ; Randomized Controlled Trials as Topic ; Statistical analysis ; Subgroups ; Surgery ; Time-to-Treatment</subject><ispartof>The Lancet (British edition), 2024-06, Vol.403 (10445), p.2693-2694</ispartof><rights>2024 Elsevier Ltd</rights><rights>2024. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1866-880ef4de5c030d73f6362bee21bf6cf6a12347914ca347e032322618d79f502a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/3070412189?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997,64387,64389,64391,72471</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38908876$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jalava, Karoliina</creatorcontrib><creatorcontrib>Sallinen, Ville</creatorcontrib><creatorcontrib>Mentula, Panu</creatorcontrib><title>Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>Short prolongation of waiting time seems to be less important than the presence of appendicolith for perforation risk; however, the predetermined power calculations did not cover this subgroup analysis, and patient-specific evaluation should be used when applying the results. A modified per-protocol analysis was performed to mitigate possible bias, and no statistically significant difference to the results was found. VS has received research grants from the Helsinki University Hospital.</description><subject>Antibiotics</subject><subject>Appendectomy</subject><subject>Appendicitis</subject><subject>Appendicitis - surgery</subject><subject>Humans</subject><subject>Older people</subject><subject>Patients</subject><subject>Preoperative Care - methods</subject><subject>Prolongation</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Statistical analysis</subject><subject>Subgroups</subject><subject>Surgery</subject><subject>Time-to-Treatment</subject><issn>0140-6736</issn><issn>1474-547X</issn><issn>1474-547X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkM9KJDEQh4O46OjuI6wEPKiHdit_Op3xIjKM7oKgqCt7C5mkGiM93W3SLczNd_ANfRJ7HPWwF09Fwff7VfER8pPBIQOmfl0Dk5CpQqh9Lg8A1LDpNTJispBZLot_62T0iWySrZTuAUAqyDfIptBj0LpQI3J7GbFpMdouPCL1WNkFDTXta9fM2yo426Gntm2x9sGFLqQj2t0hvZxenU4nN7SLwVb05emZnvTdXRPTHo3YVovv5Ftpq4Q_3uc2-Xs6vZn8zs4vzv5MTs4zx7RSmdaApfSYOxDgC1EqofgMkbNZqVypLONCFmMmnR0mguCCc8W0L8ZlDtyKbbK_6m1j89Bj6sw8JIdVZWts-mQEFIxrwdl4QHf_Q--bPtbDd0sKJONML6l8RbnYpBSxNG0McxsXhoFZijdv4s3SquHSvIk3esjtvLf3szn6z9SH6QE4XgE46HgMGE1yAWuHPkR0nfFN-OLEK9ynkRo</recordid><startdate>20240622</startdate><enddate>20240622</enddate><creator>Jalava, Karoliina</creator><creator>Sallinen, Ville</creator><creator>Mentula, Panu</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TT</scope><scope>0TZ</scope><scope>0U~</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8C2</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>KB~</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20240622</creationdate><title>Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply</title><author>Jalava, Karoliina ; Sallinen, Ville ; Mentula, Panu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1866-880ef4de5c030d73f6362bee21bf6cf6a12347914ca347e032322618d79f502a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Antibiotics</topic><topic>Appendectomy</topic><topic>Appendicitis</topic><topic>Appendicitis - surgery</topic><topic>Humans</topic><topic>Older people</topic><topic>Patients</topic><topic>Preoperative Care - methods</topic><topic>Prolongation</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Statistical analysis</topic><topic>Subgroups</topic><topic>Surgery</topic><topic>Time-to-Treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jalava, Karoliina</creatorcontrib><creatorcontrib>Sallinen, Ville</creatorcontrib><creatorcontrib>Mentula, Panu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>News PRO</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Global News & ABI/Inform Professional</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Lancet Titles</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>British Nursing Index</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Newsstand Professional</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jalava, Karoliina</au><au>Sallinen, Ville</au><au>Mentula, Panu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply</atitle><jtitle>The Lancet (British edition)</jtitle><addtitle>Lancet</addtitle><date>2024-06-22</date><risdate>2024</risdate><volume>403</volume><issue>10445</issue><spage>2693</spage><epage>2694</epage><pages>2693-2694</pages><issn>0140-6736</issn><issn>1474-547X</issn><eissn>1474-547X</eissn><abstract>Short prolongation of waiting time seems to be less important than the presence of appendicolith for perforation risk; however, the predetermined power calculations did not cover this subgroup analysis, and patient-specific evaluation should be used when applying the results. A modified per-protocol analysis was performed to mitigate possible bias, and no statistically significant difference to the results was found. VS has received research grants from the Helsinki University Hospital.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>38908876</pmid><doi>10.1016/S0140-6736(24)00640-8</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 2024-06, Vol.403 (10445), p.2693-2694 |
| issn | 0140-6736 1474-547X 1474-547X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3071283219 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Antibiotics Appendectomy Appendicitis Appendicitis - surgery Humans Older people Patients Preoperative Care - methods Prolongation Randomized Controlled Trials as Topic Statistical analysis Subgroups Surgery Time-to-Treatment |
| title | Preoperative delay in uncomplicated appendicitis: the PERFECT trial – Authors' reply |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T04%3A33%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preoperative%20delay%20in%20uncomplicated%20appendicitis:%20the%20PERFECT%20trial%20%E2%80%93%20Authors'%20reply&rft.jtitle=The%20Lancet%20(British%20edition)&rft.au=Jalava,%20Karoliina&rft.date=2024-06-22&rft.volume=403&rft.issue=10445&rft.spage=2693&rft.epage=2694&rft.pages=2693-2694&rft.issn=0140-6736&rft.eissn=1474-547X&rft_id=info:doi/10.1016/S0140-6736(24)00640-8&rft_dat=%3Cproquest_cross%3E3070412189%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3070412189&rft_id=info:pmid/38908876&rft_els_id=S0140673624006408&rfr_iscdi=true |