Controlling the STING pathway to improve immunotherapy

A genetically engineered variant of the stimulator of interferon genes (STING) protein is delivered to cancer cells, showing potential for clinical impact.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature nanotechnology 2024-06, Vol.19 (6), p.718-720
1. Verfasser:	Wilson, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	639/925 639/925/352 Animals Cancer Chemistry and Materials Science Cytokines Endoplasmic reticulum Genetic engineering Humans Immunotherapy Immunotherapy - methods Interferon Lipids Materials Science Membrane Proteins - metabolism Nanoparticles Nanotechnology Nanotechnology and Microengineering News & Views news-and-views Oncology Proteins Signal Transduction - drug effects Stimulators Vaccines
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Beschreibung
Zusammenfassung:	A genetically engineered variant of the stimulator of interferon genes (STING) protein is delivered to cancer cells, showing potential for clinical impact.
ISSN:	1748-3387 1748-3395 1748-3395
DOI:	10.1038/s41565-024-01637-x