Insights from HIV-1 vaccine and passive immunization efficacy trials

Insights from HIV-1 vaccine and passive immunization efficacy trials

An effective HIV-1 vaccine is still not available, and most vaccine efficacy trials conducted over the years resulted in no significant overall protection. Here we highlight several insights gained from these trials as well as emerging questions that may be important for further guidance to advance...

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Veröffentlicht in:Trends in molecular medicine 2024-10, Vol.30 (10), p.908-912
Hauptverfasser: Ahmed, Shamim, Herschhorn, Alon
Format: Artikel
Sprache:eng
Schlagworte:
antibody-mediated cell cytotoxicity
antibody-mediated protection
broadly neutralizing antibodies
HIV-1 vaccines
vaccine efficacy trials
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creator Ahmed, Shamim
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description An effective HIV-1 vaccine is still not available, and most vaccine efficacy trials conducted over the years resulted in no significant overall protection. Here we highlight several insights gained from these trials as well as emerging questions that may be important for further guidance to advance current research directions. An effective HIV-1 vaccine is still not available, and most vaccine efficacy trials conducted over the years resulted in no significant overall protection. Here we highlight several insights gained from these trials as well as emerging questions that may be important for further guidance to advance current research directions.
doi_str_mv 10.1016/j.molmed.2024.05.017
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subjects antibody-mediated cell cytotoxicity
antibody-mediated protection
broadly neutralizing antibodies
HIV-1 vaccines
vaccine efficacy trials
title Insights from HIV-1 vaccine and passive immunization efficacy trials
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