Design and baseline characteristics of the Finerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease (FIND-CKD) randomized trial

Design and baseline characteristics of the Finerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease (FIND-CKD) randomized trial

Finerenone, a non-steroidal mineralocorticoid receptor antagonist, improved kidney, and cardiovascular outcomes in patients with CKD and T2D in two Phase 3 outcome trials. The FIND-CKD study investigates the effect of finerenone in adults with CKD without diabetes. FIND-CKD (NCT05047263 and EU CT 20...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2024-06
Hauptverfasser: Heerspink, Hiddo J L, Agarwal, Rajiv, Bakris, George L, Cherney, David Z I, Lam, Carolyn S P, Neuen, Brendon L, Sarafidis, Pantelis A, Tuttle, Katherine R, Wanner, Christoph, Brinker, Meike D, Dizayee, Sara, Kolkhof, Peter, Schloemer, Patrick, Vesterinen, Paula, Perkovic, Vlado
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Sprache:eng
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Zusammenfassung:Finerenone, a non-steroidal mineralocorticoid receptor antagonist, improved kidney, and cardiovascular outcomes in patients with CKD and T2D in two Phase 3 outcome trials. The FIND-CKD study investigates the effect of finerenone in adults with CKD without diabetes. FIND-CKD (NCT05047263 and EU CT 2023-506897-11-00) is a randomized, double-blind, placebo-controlled Phase 3 trial in patients with CKD of non-diabetic aetiology. Adults with a urinary albumin-creatinine ratio (UACR) of ≥ 200 to ≤3500 mg/g and eGFR ≥ 25 to
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfae132