Association and prediction of Life's Essential 8 score, genetic susceptibility with MCI, dementia, and MRI indices: A prospective cohort study

To examine the associations of Life's Essential 8 (LE8) and its predictive performance with mild cognitive impairment (MCI), dementia and brain MRI indices. We used cohort data from UK Biobank. LE8 was categorized into low (

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Veröffentlicht in:Journal of affective disorders 2024-09, Vol.360, p.394-402
Hauptverfasser: Wang, Qi, Yu, Ruihong, Dong, Caiyun, Zhou, Chunmiao, Xie, Ziwei, Sun, Huizi, Fu, Chunying, Zhu, Dongshan
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Sprache:eng
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Zusammenfassung:To examine the associations of Life's Essential 8 (LE8) and its predictive performance with mild cognitive impairment (MCI), dementia and brain MRI indices. We used cohort data from UK Biobank. LE8 was categorized into low (
ISSN:0165-0327
1573-2517
1573-2517
DOI:10.1016/j.jad.2024.06.008