Validation of a clinical breast cancer risk assessment tool combining a polygenic score for all ancestries with traditional risk factors
We previously described a combined risk score (CRS) that integrates a multiple-ancestry polygenic risk score (MA-PRS) with the Tyrer-Cuzick (TC) model to assess breast cancer (BC) risk. Here, we present a longitudinal validation of CRS in a real-world cohort. This study included 130,058 patients ref...
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Veröffentlicht in: | Genetics in medicine 2024-07, Vol.26 (7), p.101128, Article 101128 |
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