Epidemiological surveillance of acute respiratory infections based on targeted metagenomic next generation sequencing during the flu season after COVID-19 pandemic in Beijing

•During flu season, large-scale multicenter ARI surveillance conducted with tNGS.•tNGS achieved 80.80% positivity, with bacteria at 53.76% and RNA viruses at 76.24%.•Positivity rates for IAV and IBV: 22.16% and 25.28%, showing distinct trends.•Exactly 34.4% samples show mixed infections, primarily b...

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Veröffentlicht in:	The Journal of infection 2024-07, Vol.89 (1), p.106188, Article 106188
Hauptverfasser:	Han, Bing, Li, Xu-ming, Li, Ran, Ning, Wu, Zhang, Yuan-yuan, Tang, Yan-fen, Zhang, Ye, Hu, Long, Li, Jian-dong, Liu, Gang, Zhang, Dan, Gu, Li, Xia, Han, Wang, Xi, Jiang, Rong-meng
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Zusammenfassung:	•During flu season, large-scale multicenter ARI surveillance conducted with tNGS.•tNGS achieved 80.80% positivity, with bacteria at 53.76% and RNA viruses at 76.24%.•Positivity rates for IAV and IBV: 22.16% and 25.28%, showing distinct trends.•Exactly 34.4% samples show mixed infections, primarily bacterial and viral (25.84%).
ISSN:	0163-4453 1532-2742 1532-2742
DOI:	10.1016/j.jinf.2024.106188