Periodontal inflammatory and microbial profiles in healthy young African Americans and Caucasians

Aim This study aimed to compare microbial and inflammatory profiles in periodontally/systemically healthy African American (AA) and Caucasian (C) individuals. Materials and Methods Thirty‐seven C and 46 AA aged from 5 to 25 years were evaluated regarding periodontal disease, caries, microbial subgingival profile via 16‐s sequencing, as well as salivary and gingival crevicular fluid (GCF) inflammatory profile via multiplex assay. Results Greater probing depth percentage was detected in AA (p = .0075), while a higher percentage of caries index (p = .0069) and decayed, missing, filled teeth (DMFT) index (p = .0089) was observed in C, after adjusting for number of teeth, sex and age. Salivary levels of IL‐6, IL‐8 and TNFα were higher for C, whereas GCF levels of eotaxin, IL‐12p40, IL‐12p70, IL‐2 and MIP‐1α were higher in AA (p