H2O2-triggered CO release based on porphyrinic covalent organic polymers for photodynamic/gas synergistic therapy

H2O2-triggered CO release based on porphyrinic covalent organic polymers for photodynamic/gas synergistic therapy

A novel H2O2-responsive carbon monoxide nanogenerator was designed by effectively encapsulating a manganese carbonyl prodrug into porphyrinic covalent organic polymers for realizing the combined CO gas and photodynamic therapy under near infrared light irradiation.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2024-05, Vol.60 (45), p.5864-5867
Hauptverfasser: Wang, Yang, Liang, Xufeng, An, Jian, Pu, Jia, Meng, Yujia, Bai, Yiqiao, Yu, Wenqiang, Gao, Yunhan, Chen, Tingting, Yao, Yong
Format: Artikel
Sprache:eng
Schlagworte:
Carbon monoxide
Carbonyls
Hydrogen peroxide
Light irradiation
Manganese
Nanogenerators
Polymers
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Zusammenfassung:A novel H2O2-responsive carbon monoxide nanogenerator was designed by effectively encapsulating a manganese carbonyl prodrug into porphyrinic covalent organic polymers for realizing the combined CO gas and photodynamic therapy under near infrared light irradiation.
ISSN:1359-7345
1364-548X
DOI:10.1039/d4cc01485e