Gas‐Responsive and Gas‐Releasing Polymer Assemblies

In order to explore the unique physiological roles of gas signaling molecules and gasotransmitters in vivo, chemists have engineered a variety of gas‐responsive polymers that can monitor their changes in cellular milieu, and gas‐releasing polymers that can orchestrate the release of gases. These have advanced their potential applications in the field of bio‐imaging, nanodelivery, and theranostics. Since these polymers are of different chain structures and properties, the morphology of their assemblies will manifest distinct transitions after responding to gas or releasing gas. In this review, we summarize the fundamental design rationale of gas‐responsive and gas‐releasing polymers in structure and their controlled transition in self‐assembled morphology and function, as well as present some perspectives in this prosperous field. Emerging challenges faced for the future research are also discussed. Gas signaling molecules can act as stimuli or as releasers to influence the morphological transformation and function of polymer assemblies for diagnostic and therapeutic purposes. This review summarizes the fundamental design rationale of gas‐responsive and gas‐releasing polymers in structure and their controllable transitions in self‐assembled morphology and function.