Peri‐implant diseases and systemic inflammation: A preliminary analysis from a cross‐sectional survey of patients with hypertension

Background The aim of this study was to investigate the association between peri‐implant diseases and systemic inflammation assessed by serum C‐reactive protein (CRP) levels in a sample of patients with hypertension. Methods A total of 151 participants with hypertension were included in a cross‐sectional study. The population was divided into six groups according to their peri‐implant and periodontal status (healthy controls, mucositis, peri‐implantitis, periodontitis, periodontitis and mucositis, periodontitis, and peri‐implantitis). Linear, logistic regression, and correlation analyses were performed. Results CRP levels were statistically significantly higher in participants with periodontitis alone (median 3.2 mg/L, interquartile range [IQR] 1.8, p = 0.012), combined with mucositis (3.10 mg/L, IQR 2.35, p 3 mg/L (odds ratio = 7.3, 95% confidence interval 1.6–33.9). Conclusions Peri‐implant diseases are associated with systemic inflammation, but the nature of the association should be further investigated.