Keratosis Pilaris–Like Reaction Associated With Chromatin Remodeling Complex Inhibition in Uveal Melanoma

Keratosis Pilaris–Like Reaction Associated With Chromatin Remodeling Complex Inhibition in Uveal Melanoma

This case series describes a constellation of novel adverse reactions in 3 of 9 patients with uveal melanoma receiving treatment targeting activity of the Brahma-associated factor chromatin remodeling complex.

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Bibliographische Detailangaben
Veröffentlicht in:Archives of dermatology (1960) 2024-06, Vol.160 (6), p.682-685
Hauptverfasser: Seervai, Riyad N. H, Taylor, Madison M, Rahbar, Ziba, Patel, Sapna P, Nelson, Kelly C, Prieto, Victor G, Curry, Jonathan L
Format: Artikel
Sprache:eng
Schlagworte:
Abnormalities, Multiple
Cell growth
Chromatin Assembly and Disassembly
Darier Disease - diagnosis
Darier Disease - pathology
Eye cancer
Eyebrows - abnormalities
Female
Humans
Inhibitor drugs
Male
Melanoma - pathology
Metastasis
Middle Aged
Transcription Factors - genetics
Uveal Neoplasms - genetics
Uveal Neoplasms - pathology
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Beschreibung
Zusammenfassung:This case series describes a constellation of novel adverse reactions in 3 of 9 patients with uveal melanoma receiving treatment targeting activity of the Brahma-associated factor chromatin remodeling complex.
ISSN:2168-6068
2168-6084
2168-6084
DOI:10.1001/jamadermatol.2024.1137