Multimaterial 3D Laser Printing of Cell‐Adhesive and Cell‐Repellent Hydrogels

Here, a straightforward method is reported for manufacturing 3D microstructured cell‐adhesive and cell‐repellent multimaterials using two‐photon laser printing. Compared to existing strategies, this approach offers bottom‐up molecular control, high customizability, and rapid and precise 3D fabricati...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2024-08, Vol.20 (33), p.e2401344-n/a
Hauptverfasser: Schwegler, Niklas, Gebert, Tanisha, Villiou, Maria, Colombo, Federico, Schamberger, Barbara, Selhuber‐Unkel, Christine, Thomas, Franziska, Blasco, Eva
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Sprache:eng
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Zusammenfassung:Here, a straightforward method is reported for manufacturing 3D microstructured cell‐adhesive and cell‐repellent multimaterials using two‐photon laser printing. Compared to existing strategies, this approach offers bottom‐up molecular control, high customizability, and rapid and precise 3D fabrication. The printable cell‐adhesive polyethylene glycol (PEG) based material includes an Arg‐Gly‐Asp (RGD) containing peptide synthesized through solid‐phase peptide synthesis, allowing for precise control of the peptide design. Remarkably, minimal amounts of RGD peptide (
ISSN:1613-6810
1613-6829
1613-6829
DOI:10.1002/smll.202401344