Antibiotic duration and gastric dysmotility in preterm neonates

Antibiotic duration and gastric dysmotility in preterm neonates

Prolonged antibiotic use after birth is associated with neonatal feeding intolerance and functional gastrointestinal disorders (FGIDs). A gastric dysrhythmia (tachygastria) with frequencies >4-9 cycles per minute, measured by electrogastrography (EGG), is associated with FGIDs. The relationship b...

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Veröffentlicht in:Journal of pediatric gastroenterology and nutrition 2024-09, Vol.79 (3), p.533-540
Hauptverfasser: Sadder, Liane Samira, Brown, Larry Steven, Roblyer, Lindsay, Sanghavi, Rinarani, Ortigoza, Eric Brum
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - administration & dosage
Female
Gastrointestinal Motility - drug effects
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Longitudinal Studies
Male
Prospective Studies
Time Factors
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Zusammenfassung:Prolonged antibiotic use after birth is associated with neonatal feeding intolerance and functional gastrointestinal disorders (FGIDs). A gastric dysrhythmia (tachygastria) with frequencies >4-9 cycles per minute, measured by electrogastrography (EGG), is associated with FGIDs. The relationship between prolonged antibiotic use and % time spent in tachygastria is unknown in preterm infants. We aimed to compare weekly changes in % tachygastria between preterm infants receiving long (>48 h) versus short (≤48 h) courses of antibiotics for early onset sepsis evaluation (initiated at
ISSN:0277-2116
1536-4801
1536-4801
DOI:10.1002/jpn3.12235