Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation

Lung adenocarcinoma (LUAD), a type of non-small cell lung cancer (NSCLC), originates from not only bronchial epithelial cells but also alveolar type 2 (AT2) cells, which could differentiate into AT2-like cells. AT2-like cells function as cancer stem cells (CSCs) of LUAD tumorigenesis to give rise to...

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Veröffentlicht in:	Cancer letters 2024-06, Vol.592, p.216922, Article 216922
Hauptverfasser:	He, Qiangqiang, Qu, Meiyu, Xu, Chengyun, Wu, Lichao, Xu, Yana, Su, Jiakun, Bao, Hangyang, Shen, Tingyu, He, Yangxun, Cai, Jibao, Xu, Da, Zeng, Ling-Hui, Wu, Ximei
Format:	Artikel
Sprache:	eng
Schlagworte:	AT2 cell CCNA2 Lung adenocarcinoma Smoking WNT/β-catenin
Online-Zugang:	Volltext
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