Basal Hyperglycemia Contributes More Than 50% to Time in Range in Pregnant Women With Type 1 Diabetes

Abstract Objectives To evaluate the relative contribution of basal hyperglycemia (BHG) and postprandial hyperglycemia (PHG) to the time in range (TIR) categories and adverse pregnancy outcomes in pregnant women with type 1 diabetes mellitus (T1DM). Materials and Methods This observational study incl...

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Veröffentlicht in:The journal of clinical endocrinology and metabolism 2024-11, Vol.109 (12), p.3264-3271
Hauptverfasser: Ling, Ping, Yang, Daizhi, Wang, Chaofan, Zheng, Xueying, Luo, Sihui, Yang, Xubin, Deng, Hongrong, Xu, Wen, Yan, Jinhua, Weng, Jianping
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Sprache:eng
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Zusammenfassung:Abstract Objectives To evaluate the relative contribution of basal hyperglycemia (BHG) and postprandial hyperglycemia (PHG) to the time in range (TIR) categories and adverse pregnancy outcomes in pregnant women with type 1 diabetes mellitus (T1DM). Materials and Methods This observational study included 112 pregnancies with T1DM from the CARNATION study who wore continuous glucose monitoring (CGM) devices during pregnancy. The data from CGM were analyzed for TIR (range, 3.5-7.8 mmol/L), areas under the curve of PHG, area under the curve of BHG, and BHG and PHG contribution rates. The contribution rates of BHG and PHG to the different levels of TIR (
ISSN:0021-972X
1945-7197
1945-7197
DOI:10.1210/clinem/dgae291