Convergence and divergence in Kawasaki disease and multisystem inflammatory syndrome in children: results from the COVASAKI survey

To compare Kawasaki disease (KD) and multisystem inflammatory syndrome (MIS-C) in children. Prospective collection of demographics, clinical and treatment data. Assessment of type 1 interferon (IFN) score, CXCL9, CXCL10, Interleukin (IL)18, IFNγ, IL6, IL1b at disease onset and at recovery. 87 patien...

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Veröffentlicht in:	Clinical and experimental rheumatology 2024-04, Vol.42 (4), p.931-936
Hauptverfasser:	Mastrolia, Maria Vincenza, Martini, Marco, Memmini, Graziano, Ferrara, Giovanna, Bernardini, Roberto, Peroni, Diego, Consolini, Rita, Marrani, Edoardo, Agostiniani, Rino, Maccora, Ilaria, Falorni, Susanna, Azzari, Chiara, Calabri, Giovanni Battista, Pagnini, Ilaria, Indolfi, Giuseppe, L'Erario, Manuela, Trapani, Sandra, Simonini, Gabriele
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - blood Child Child, Preschool COVID-19 - complications COVID-19 - diagnosis Female Humans Infant Male Mucocutaneous Lymph Node Syndrome - complications Mucocutaneous Lymph Node Syndrome - diagnosis Mucocutaneous Lymph Node Syndrome - epidemiology Mucocutaneous Lymph Node Syndrome - physiopathology Prospective Studies Systemic Inflammatory Response Syndrome - diagnosis Systemic Inflammatory Response Syndrome - epidemiology
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Zusammenfassung:	To compare Kawasaki disease (KD) and multisystem inflammatory syndrome (MIS-C) in children. Prospective collection of demographics, clinical and treatment data. Assessment of type 1 interferon (IFN) score, CXCL9, CXCL10, Interleukin (IL)18, IFNγ, IL6, IL1b at disease onset and at recovery. 87 patients (43 KD, 44 MIS-C) were included. Age was higher in MIS-C compared to KD group (mean 31±23 vs. 94±50 months, p
ISSN:	0392-856X 1593-098X 1593-098X
DOI:	10.55563/clinexprheumatol/l64q51