Switchable Enantioselectivity in Conjugate Alkyne Addition of β,γ-Unsaturated α‑Keto Esters by Asymmetric Binary Acid Catalysis

Switchable Enantioselectivity in Conjugate Alkyne Addition of β,γ-Unsaturated α‑Keto Esters by Asymmetric Binary Acid Catalysis

Switchable enantioselectivity was uncovered in the enantioselective catalytic conjugate addition of β,γ-unsaturated α-keto esters with terminal alkynes to the chiral Lewis acid complex of In­(BF4)3 and chiral phosphoric acid.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2024-05, Vol.26 (17), p.3612-3616
Hauptverfasser: Duan, Depeng, Tang, Mengdie, Wang, Man, Qiu, Huixin, Song, Ran, Yang, Daoshan, Lv, Jian
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Switchable enantioselectivity was uncovered in the enantioselective catalytic conjugate addition of β,γ-unsaturated α-keto esters with terminal alkynes to the chiral Lewis acid complex of In­(BF4)3 and chiral phosphoric acid.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.4c01101