Potential correlation between anti-laminin 332 autoantibodies and malignant tumours in anti-BP180-type mucous membrane pemphigoid

To the best of our knowledge, this is the first large cohort study to analyse the potential correlations between anti-laminin (LM) 332 autoantibodies and malignant tumours in 520 patients with anti-BP180-type mucous membrane pemphigoid (BP180-MMP) recruited from four countries in two continents. Patients who were anti-LM332 autoantibody (–) with BP180-MMP were used as a control group. The results in this study support that anti-LM332 autoantibodies are positively correlated with malignant tumours in people with BP180-MMP, particularly in Europe.