Effectiveness of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease among children <2 years old: A prospective population-based study in rural Bangladesh

Effectiveness of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease among children <2 years old: A prospective population-based study in rural Bangladesh

The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in March 2015 in Bangladesh. In this study, we aimed to estimate the impact of PCV10 on invasive pneumococcal disease (IPD) identified by blood cultures and severe pneumonia identified clinically and its effectiveness on invasive di...

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Veröffentlicht in:Vaccine 2024-01, Vol.42 (2), p.255-262
Hauptverfasser: Malaker, Roly, Hasanuzzaman, Md, Hooda, Yogesh, Rahman, Hafizur, Chandra Das, Rajib, Kanon, Naito, Saha, Senjuti, Tanmoy, Arif M., Ranjan Chakraborty, Sowmitra, Saha, Shampa, Islam, Maksuda, Darmstadt, Gary L., Baqui, Abdullah H., Sathosam, Mathuram, El-Arifeen, Shams, Whitney, Cynthia G., Saha, Samir K.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Bangladesh
Bangladesh - epidemiology
Blood
Blood culture
Breastfeeding & lactation
Child, Preschool
Children
Children & youth
Childrens health
Cohort analysis
Conjugates
Consciousness
Disease
Effectiveness
Fever
Guardians
Health surveillance
Hospitals
Humans
Immunization
Incidence
Indirect cohort
Infant
Invasive pneumococcal disease
Meningitis
monitoring
PCV10
Pneumococcal Infections - epidemiology
Pneumococcal Infections - prevention & control
Pneumococcal Vaccines - therapeutic use
Pneumonia
Population
Population studies
Prospective Studies
Respiration
Sepsis
Serogroup
Serotypes
Streptococcus infections
Streptococcus pneumoniae
Surveillance
vaccination
Vaccine efficacy
Vaccine impact
Vaccines
Vaccines, Conjugate - therapeutic use
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Beschreibung
Zusammenfassung:The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in March 2015 in Bangladesh. In this study, we aimed to estimate the impact of PCV10 on invasive pneumococcal disease (IPD) identified by blood cultures and severe pneumonia identified clinically and its effectiveness on invasive disease caused by vaccine serotypes. We conducted population-based surveillance among children aged 2-
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2023.12.007