Sacral-Nerve-Sparing Planning Strategy in Pelvic Sarcomas/Chordomas Treated with Carbon-Ion Radiotherapy

To minimize radiation-induced lumbosacral neuropathy (RILSN), we employed sacral-nerve-sparing optimized carbon-ion therapy strategy (SNSo-CIRT) in treating 35 patients with pelvic sarcomas/chordomas. Plans were optimized using Local Effect Model-I (LEM-I), prescribed D (median dose to HD-PTV) = 73....

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Veröffentlicht in:	Cancers 2024-04, Vol.16 (7), p.1284
Hauptverfasser:	Nachankar, Ankita, Schafasand, Mansure, Hug, Eugen, Martino, Giovanna, Góra, Joanna, Carlino, Antonio, Stock, Markus, Fossati, Piero
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbon Chemotherapy Denosumab Diabetes Ethics Hypoxia Medical imaging Medical prognosis Morbidity Nerves Neuropathy Patients Planning Radiation therapy Radiotherapy Sacrum Sarcoma Sciatic nerve Surgery Survival Toxicity Tumors
Online-Zugang:	Volltext
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