A successful desensitization in an adult patient with ARA-C infusion reaction

Introduction Cytarabine (ARA-C) is an antimetabolite agent used especially in the treatment of hematologic malignancies. Infusion reactions have an important place among the side effects that may occur due to treatment. Clinical findings of infusion reactions resemble allergic reactions. Case Report 47-year-old male patient with a diagnosis of B-cell Acute Lymphoblastic Leukaemia developed infusion reaction during ARA-C treatment. Management & Outcome There was no alternative treatment option for his existing malignant disease, we decided ARA-C desensitization. Discussion We would like to describe a successful desensitization protocol in an adult patient who experienced a reaction during ARA-C infusion.