Donor-recipient race-ethnicity concordance and patient survival after liver transplantation

We assessed the association between patient survival after liver transplantation (LT) and donor-recipient race-ethnicity (R/E) concordance. The Scientific Registry of Transplant Recipients (SRTR) was retrospectively analyzed using data collected between 2002 and 2019. Only adults without history of...

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Veröffentlicht in:HPB (Oxford, England) England), 2024-06, Vol.26 (6), p.772-781
Hauptverfasser: Laffey, Makenna, Ashwat, Eishan, Lui, Hao, Zhang, Xingyu, Kaltenmeier, Christof, Packiaraj, Godwin, Crane, Andrew, Alshamery, Sarmad, Gunabushanam, Vikraman, Ganoza, Armando, Dharmayan, Stalin, Powers, Colin A., Jonassaint, Naudia, Molinari, Michele
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Sprache:eng
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Zusammenfassung:We assessed the association between patient survival after liver transplantation (LT) and donor-recipient race-ethnicity (R/E) concordance. The Scientific Registry of Transplant Recipients (SRTR) was retrospectively analyzed using data collected between 2002 and 2019. Only adults without history of prior organ transplant and recipients of LT alone were included. The primary outcome was patient survival. Donors and recipients were categorized into five R/E groups: White/Caucasian, African American/Black, Hispanic/Latino, Asian, and Others. Statistical analyses were performed using Kaplan–Meier survival curves and Cox Proportional Hazards models, adjusting for donor and recipient covariates. 85,427 patients were included. Among all the R/E groups, Asian patients had the highest 5-year survival (81.3%; 95% CI = 79.9–82.7), while African American/Black patients had the lowest (71.4%; 95% CI = 70.3–72.6) (P 
ISSN:1365-182X
1477-2574
1477-2574
DOI:10.1016/j.hpb.2024.03.003